More often than I would think, my hiking pals and I stumble upon old, abandoned whiskey stills when we're bushwhacking through the mountains looking for new waterfalls or trying to find our ways to the tops of isolated summits that don't have trails.
Last winter, on a hike to find the elusive Sally Queen Falls, we stumbled upon just such an abandoned still. This one looked to have been last used many, many years ago. These mountains are full of old roads that were probably passable as late as the early 1960s, but which are now not even recognizable as road beds.
The still here was probably pretty high volume, so they'd have needed road access to be nearby, even if they were able to haul out gallons of this stuff by hand or by pack horse.
Anyway, the southern Appalachians are packed with these old sites.